Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.1
USERS' SCORE
Good
Based on 30 Reviews
8.4
Supplement Facts
Serving Size: 2 Softgels
Amount Per Serving
%DV
Calories
20
Total Fat
2 g
3%**
Saturated Fat
0.5 g
3%**
Polyunsaturated Fat
1 g
†
Monounsaturated Fat
0.5 g
†
Fish Oil Concentrate
2 g (2,000 mg)
†
Eicosapentaenoic Acid (EPA)
360 mg
†
Docosahexaenoic Acid (DHA)
240 mg
†
Top Medical Research Studies
We explored whether purified docosahexaenoic acid (DHA), an omega-3 fatty acid, can ease knee pain and swelling in a mouse model of arthritis. Mice with arthritis were treated with either oral or injected DHA, and we observed notable improvements in pain behavior and knee swelling.
This study highlights that DHA may reduce pain and inflammation in knee arthritis, suggesting it could be a helpful option for those suffering from rheumatoid arthritis. However, it’s essential to keep in mind that these results come from an animal model, and human studies are necessary.
This study highlights that DHA may reduce pain and inflammation in knee arthritis, suggesting it could be a helpful option for those suffering from rheumatoid arthritis. However, it’s essential to keep in mind that these results come from an animal model, and human studies are necessary.
Read More
8
Omega-3 reduces knee pain effectively
We conducted a rigorous clinical trial to investigate how omega-3 fish oil affects knee pain in people aged 40 and older. In this double-blind study with four groups, we found that those taking an omega-3-based product, AvailOm, experienced a notable reduction in pain intensity compared to a placebo.
By week eight, participants reported less discomfort and improved quality of life. Additionally, the intake of AvailOm led to better muscle strength and sleep quality, making it a promising option for alleviating persistent knee pain. Overall, omega-3 fish oil shows effective benefits for older adults struggling with knee pain.
By week eight, participants reported less discomfort and improved quality of life. Additionally, the intake of AvailOm led to better muscle strength and sleep quality, making it a promising option for alleviating persistent knee pain. Overall, omega-3 fish oil shows effective benefits for older adults struggling with knee pain.
Read More
8
Fish oil improves knee function
We explored the effects of omega-3 fish oil on knee osteoarthritis by evaluating 75 participants over 8 weeks. Divided into three groups, they took either 1,000 mg or 2,000 mg of fish oil each day.
Our findings showed that both dosages improved knee function and pain relief compared to a control group. However, the higher dose of 2,000 mg did not provide additional benefits over the 1,000 mg dose. Overall, participants reported high satisfaction with their results, and the treatment was deemed safe with minimal side effects.
Our findings showed that both dosages improved knee function and pain relief compared to a control group. However, the higher dose of 2,000 mg did not provide additional benefits over the 1,000 mg dose. Overall, participants reported high satisfaction with their results, and the treatment was deemed safe with minimal side effects.
Read More
Most Useful Reviews
8.5
Back pain relief
90 people found this helpful
I’ve been taking this vitamin for a month now. My lower back pain from work has disappeared. The quality of life is worth the money.
Read More
8.5
Strengthened feeling
90 people found this helpful
After taking this vitamin for lower back pain, I woke up feeling stronger than ever the next day!
Read More
9
Headache reduction
3 people found this helpful
The neurologist prescribed this for headaches. After three weeks, the frequency of pain decreased, and I forgot about it entirely.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.1
- All Researches
9.5
Phytalgic promotes knee pain relief
We evaluated the effectiveness of Phytalgic, a supplement containing fish oil, on reducing knee pain in patients with osteoarthritis. In a randomized double-blind study of 81 participants, those taking Phytalgic reported lower usage of analgesics and NSAIDs compared to the placebo group.
Our findings showed significant reductions in pain, stiffness, and overall knee function, highlighting the potential benefit of Phytalgic in managing osteoarthritis symptoms. Overall, it seems that Phytalgic may offer an alternative relief option for those suffering from knee pain.
Our findings showed significant reductions in pain, stiffness, and overall knee function, highlighting the potential benefit of Phytalgic in managing osteoarthritis symptoms. Overall, it seems that Phytalgic may offer an alternative relief option for those suffering from knee pain.
Read More
We explored whether purified docosahexaenoic acid (DHA), an omega-3 fatty acid, can ease knee pain and swelling in a mouse model of arthritis. Mice with arthritis were treated with either oral or injected DHA, and we observed notable improvements in pain behavior and knee swelling.
This study highlights that DHA may reduce pain and inflammation in knee arthritis, suggesting it could be a helpful option for those suffering from rheumatoid arthritis. However, it’s essential to keep in mind that these results come from an animal model, and human studies are necessary.
This study highlights that DHA may reduce pain and inflammation in knee arthritis, suggesting it could be a helpful option for those suffering from rheumatoid arthritis. However, it’s essential to keep in mind that these results come from an animal model, and human studies are necessary.
Read More
9
We conducted a comprehensive study involving 177 patients with moderate to severe osteoarthritis (OA) affecting their hips or knees. Over 26 weeks, participants were divided into two groups. One group received glucosamine sulfate combined with omega-3 fatty acids, specifically eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). The other group was treated with glucosamine sulfate alone.
Our main focus was to determine whether the combined treatment provided any notable benefits over glucosamine alone when it came to easing knee pain. We used the WOMAC score to assess pain, stiffness, and overall function in the participants. When we looked at the significant reduction of pain, more than 92% from both groups experienced some relief, but the combination treatment showed a higher response rate of 44%, compared to 32% in the glucosamine-only group.
Although both treatments appeared safe over the study duration, the statistical differences indicate that adding omega-3s can be beneficial for those specifically hoping for greater relief. We also noted that symptoms like morning stiffness and knee pain showed improvements, with greater reductions in the group taking the combination treatment. This suggests that eicosapentaenoic acid may provide added value in managing knee pain due to osteoarthritis, particularly for patients looking to maximize their treatment benefits.
Our main focus was to determine whether the combined treatment provided any notable benefits over glucosamine alone when it came to easing knee pain. We used the WOMAC score to assess pain, stiffness, and overall function in the participants. When we looked at the significant reduction of pain, more than 92% from both groups experienced some relief, but the combination treatment showed a higher response rate of 44%, compared to 32% in the glucosamine-only group.
Although both treatments appeared safe over the study duration, the statistical differences indicate that adding omega-3s can be beneficial for those specifically hoping for greater relief. We also noted that symptoms like morning stiffness and knee pain showed improvements, with greater reductions in the group taking the combination treatment. This suggests that eicosapentaenoic acid may provide added value in managing knee pain due to osteoarthritis, particularly for patients looking to maximize their treatment benefits.
Read More
8
Omega-3 reduces knee pain effectively
We conducted a rigorous clinical trial to investigate how omega-3 fish oil affects knee pain in people aged 40 and older. In this double-blind study with four groups, we found that those taking an omega-3-based product, AvailOm, experienced a notable reduction in pain intensity compared to a placebo.
By week eight, participants reported less discomfort and improved quality of life. Additionally, the intake of AvailOm led to better muscle strength and sleep quality, making it a promising option for alleviating persistent knee pain. Overall, omega-3 fish oil shows effective benefits for older adults struggling with knee pain.
By week eight, participants reported less discomfort and improved quality of life. Additionally, the intake of AvailOm led to better muscle strength and sleep quality, making it a promising option for alleviating persistent knee pain. Overall, omega-3 fish oil shows effective benefits for older adults struggling with knee pain.
Read More
8
We investigated how the green-lipped mussel (GLM) can help in managing knee pain caused by osteoarthritis (OA). In our study using a rat model, we induced OA and then administered GLM to see its effects on pain and cartilage health.
Results showed that GLM significantly improved pain levels while protecting against cartilage damage and inflammation. It also reduced markers associated with destructive processes in the joints.
This suggests that GLM could be a beneficial treatment option for those suffering from OA and associated knee pain.
Results showed that GLM significantly improved pain levels while protecting against cartilage damage and inflammation. It also reduced markers associated with destructive processes in the joints.
This suggests that GLM could be a beneficial treatment option for those suffering from OA and associated knee pain.
Read More
User Reviews
USERS' SCORE
Good
Based on 30 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
8.5
Back pain relief
90 people found this helpful
I’ve been taking this vitamin for a month now. My lower back pain from work has disappeared. The quality of life is worth the money.
Read More
8.5
Strengthened feeling
90 people found this helpful
After taking this vitamin for lower back pain, I woke up feeling stronger than ever the next day!
Read More
9
Headache reduction
3 people found this helpful
The neurologist prescribed this for headaches. After three weeks, the frequency of pain decreased, and I forgot about it entirely.
Read More
9
Knee pain relief
2 people found this helpful
I started taking Omega-3 for knee pain on a rheumatologist's advice. After a month, the pain disappeared, and I feel amazing!
Read More
9
Knee pain gone
1 people found this helpful
I purchased Omega 3 upon my rheumatologist's recommendation due to my knee pain. After a month of taking two capsules daily, the pain has faded away unnoticed. I'm very pleased with the product's quality.
Read More
Frequently Asked Questions
9
Knee pain relief
2 people found this helpful
I started taking Omega-3 for knee pain on a rheumatologist's advice. After a month, the pain disappeared, and I feel amazing!
9
Knee pain gone
1 people found this helpful
I purchased Omega 3 upon my rheumatologist's recommendation due to my knee pain. After a month of taking two capsules daily, the pain has faded away unnoticed. I'm very pleased with the product's quality.
9
Knee pain improved
1 people found this helpful
After taking this supplement for a couple of months, I've noted a definite reduction in knee pain when bending or running.
8.5
Back pain relief
90 people found this helpful
I’ve been taking this vitamin for a month now. My lower back pain from work has disappeared. The quality of life is worth the money.
9
Knee pain alleviated
1 people found this helpful
As someone with advanced post-traumatic arthritis in my ankle, I found Now Foods Omega 3 to be excellent; it significantly alleviates my knee pain and enhances my mobility.
7.5
Reduced swelling
1 people found this helpful
Since I began taking Omega 3, I’ve noticed a reduction in swelling in my knees.
9
Headache reduction
3 people found this helpful
The neurologist prescribed this for headaches. After three weeks, the frequency of pain decreased, and I forgot about it entirely.
9
Effective for pain
56 people found this helpful
This is one of the best fish oil supplements I’ve tried, especially for the price! I take it alongside my vitamin D3 to address knee pain, and it’s effective in managing my inflammation.
7.5
Knee pain relief
1 people found this helpful
Our whole family takes omega; my son has used it since he was 11. I can't credit it solely since we take other supplements too, but I've stopped experiencing knee pain after years of crunching throughout my workouts. We'll continue to take this.
9
Essential supplement
When I stopped taking Omega 3, my knee pain returned. It’s a must-have supplement, although it does leave a fishy aftertaste.
8
Omega-3 reduces knee pain effectively
We conducted a rigorous clinical trial to investigate how omega-3 fish oil affects knee pain in people aged 40 and older. In this double-blind study with four groups, we found that those taking an omega-3-based product, AvailOm, experienced a notable reduction in pain intensity compared to a placebo.
By week eight, participants reported less discomfort and improved quality of life. Additionally, the intake of AvailOm led to better muscle strength and sleep quality, making it a promising option for alleviating persistent knee pain. Overall, omega-3 fish oil shows effective benefits for older adults struggling with knee pain.
By week eight, participants reported less discomfort and improved quality of life. Additionally, the intake of AvailOm led to better muscle strength and sleep quality, making it a promising option for alleviating persistent knee pain. Overall, omega-3 fish oil shows effective benefits for older adults struggling with knee pain.
8
This study focused on whether l-serine and EPA could help relieve chronic knee and low-back pain. We learned that 120 adults participated in a randomized, double-blind, placebo-controlled trial. They received either the active treatment or a placebo over an 8-week period.
After analyzing results, we found that l-serine and EPA significantly reduced pain scores. This suggests that these two substances may effectively alleviate discomfort for those suffering from persistent knee pain.
After analyzing results, we found that l-serine and EPA significantly reduced pain scores. This suggests that these two substances may effectively alleviate discomfort for those suffering from persistent knee pain.
We investigated whether krill oil could help reduce knee pain in adults experiencing mild to moderate osteoarthritis. Over six months, participants took either krill oil or a placebo in a well-structured double-blind trial.
While the results showed that krill oil was safe and led to some modest improvements in knee pain, stiffness, and physical function, the overall benefits were limited.
Thus, while krill oil may serve as a mild alternative for osteoarthritis pain relief, it’s essential to manage expectations regarding its effectiveness.
While the results showed that krill oil was safe and led to some modest improvements in knee pain, stiffness, and physical function, the overall benefits were limited.
Thus, while krill oil may serve as a mild alternative for osteoarthritis pain relief, it’s essential to manage expectations regarding its effectiveness.
We explored whether purified docosahexaenoic acid (DHA), an omega-3 fatty acid, can ease knee pain and swelling in a mouse model of arthritis. Mice with arthritis were treated with either oral or injected DHA, and we observed notable improvements in pain behavior and knee swelling.
This study highlights that DHA may reduce pain and inflammation in knee arthritis, suggesting it could be a helpful option for those suffering from rheumatoid arthritis. However, it’s essential to keep in mind that these results come from an animal model, and human studies are necessary.
This study highlights that DHA may reduce pain and inflammation in knee arthritis, suggesting it could be a helpful option for those suffering from rheumatoid arthritis. However, it’s essential to keep in mind that these results come from an animal model, and human studies are necessary.
8
Fish oil improves knee function
We explored the effects of omega-3 fish oil on knee osteoarthritis by evaluating 75 participants over 8 weeks. Divided into three groups, they took either 1,000 mg or 2,000 mg of fish oil each day.
Our findings showed that both dosages improved knee function and pain relief compared to a control group. However, the higher dose of 2,000 mg did not provide additional benefits over the 1,000 mg dose. Overall, participants reported high satisfaction with their results, and the treatment was deemed safe with minimal side effects.
Our findings showed that both dosages improved knee function and pain relief compared to a control group. However, the higher dose of 2,000 mg did not provide additional benefits over the 1,000 mg dose. Overall, participants reported high satisfaction with their results, and the treatment was deemed safe with minimal side effects.
3
We examined whether high-dose fish oil could better relieve knee osteoarthritis symptoms than a low dose. In a thorough trial involving 202 participants, they were divided into groups receiving either high-dose (4.5 g omega-3) or low-dose fish oil (0.45 g omega-3) for up to two years.
While both groups experienced some improvement in knee pain and function, the low-dose group responded better overall. There was no significant difference in cartilage loss or other health outcomes, leading us to conclude that higher doses may not be more effective and warrant further research into alternative oil blends.
While both groups experienced some improvement in knee pain and function, the low-dose group responded better overall. There was no significant difference in cartilage loss or other health outcomes, leading us to conclude that higher doses may not be more effective and warrant further research into alternative oil blends.
References
- Pérez-Piñero S, Muñoz-Carrillo JC, Victoria-Montesinos D, García-Muñoz AM, Andreu-Caravaca L, et al. Efficacy of Extract and/or an Omega-3-Based Product for Improving Pain and Function in People Older Than 40 Years with Persistent Knee Pain: A Randomized Double-Blind Controlled Clinical Trial. Nutrients. 2023;15. 10.3390/nu15173848
- Stonehouse W, Benassi-Evans B, Bednarz J, Vincent AD, Hall S, et al. Krill oil improved osteoarthritic knee pain in adults with mild to moderate knee osteoarthritis: a 6-month multicenter, randomized, double-blind, placebo-controlled trial. Am J Clin Nutr. 2022;116:672. 10.1093/ajcn/nqac125
- Jhun J, Na HS, Cho KH, Kim J, Moon YM, et al. A green-lipped mussel reduces pain behavior and chondrocyte inflammation and attenuated experimental osteoarthritis progression. PLoS One. 2021;16:e0259130. 10.1371/journal.pone.0259130
- VanDusseldorp TA, Escobar KA, Johnson KE, Stratton MT, Moriarty T, et al. Impact of Varying Dosages of Fish Oil on Recovery and Soreness Following Eccentric Exercise. Nutrients. 2020;12. 10.3390/nu12082246
- Sasahara I, Yamamoto A, Takeshita M, Suga Y, Suzuki K, et al. l-Serine and EPA Relieve Chronic Low-Back and Knee Pain in Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. J Nutr. 2020;150:2278. 10.1093/jn/nxaa156
- Valdes AM, Ravipati S, Menni C, Abhishek A, Metrustry S, et al. Association of the resolvin precursor 17-HDHA, but not D- or E- series resolvins, with heat pain sensitivity and osteoarthritis pain in humans. Sci Rep. 2017;7:10748. 10.1038/s41598-017-09516-3
- Sibille KT, King C, Garrett TJ, Glover TL, Zhang H, et al. Omega-6: Omega-3 PUFA Ratio, Pain, Functioning, and Distress in Adults With Knee Pain. Clin J Pain. 2018;34:182. 10.1097/AJP.0000000000000517
- Peanpadungrat P. Efficacy and Safety of Fish Oil in Treatment of Knee Osteoarthritis. J Med Assoc Thai. 2015;98 Suppl 3:S110.
- Hill CL, March LM, Aitken D, Lester SE, Battersby R, et al. Fish oil in knee osteoarthritis: a randomised clinical trial of low dose versus high dose. Ann Rheum Dis. 2016;75:23. 10.1136/annrheumdis-2014-207169
- Torres-Guzman AM, Morado-Urbina CE, Alvarado-Vazquez PA, Acosta-Gonzalez RI, Chávez-Piña AE, et al. Chronic oral or intraarticular administration of docosahexaenoic acid reduces nociception and knee edema and improves functional outcomes in a mouse model of Complete Freund's Adjuvant-induced knee arthritis. Arthritis Res Ther. 2014;16:R64. 10.1186/ar4502
- Jacquet A, Girodet PO, Pariente A, Forest K, Mallet L, et al. Phytalgic, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip: a randomised double-blind placebo-controlled clinical trial. Arthritis Res Ther. 2009;11:R192. 10.1186/ar2891
- Tartibian B, Maleki BH, Abbasi A. The effects of ingestion of omega-3 fatty acids on perceived pain and external symptoms of delayed onset muscle soreness in untrained men. Clin J Sport Med. 2009;19:115. 10.1097/JSM.0b013e31819b51b3
- Kubo Y, Ikeya M, Sugiyama S, Takachu R, Tanaka M, et al. Effects of n-3 polyunsaturated fatty acid supplementation on quadriceps weakness immediately after total knee arthroplasty: a pilot, randomized, open-label clinical trial. J Phys Ther Sci. 2023;35:93. 10.1589/jpts.35.93
- Kubo Y, Sugiyama S, Takachu R, Tanaka M, Ikeya M, et al. Association between serum n-3 polyunsaturated fatty acids and quadriceps weakness immediately after total knee arthroplasty. PLoS One. 2020;15:e0228460. 10.1371/journal.pone.0228460
- Gruenwald J, Petzold E, Busch R, Petzold HP, Graubaum HJ. Effect of glucosamine sulfate with or without omega-3 fatty acids in patients with osteoarthritis. Adv Ther. 2009;26:858. 10.1007/s12325-009-0060-3
- Iverson C, Bacong A, Liu S, Baumgartner S, Lundström T, et al. Omega-3-carboxylic acids provide efficacious anti-inflammatory activity in models of crystal-mediated inflammation. Sci Rep. 2018;8:1217. 10.1038/s41598-018-19252-x
- Huang J, Burston JJ, Li L, Ashraf S, Mapp PI, et al. Targeting the D Series Resolvin Receptor System for the Treatment of Osteoarthritis Pain. Arthritis Rheumatol. 2017;69:996. 10.1002/art.40001
- Barden AE, Moghaddami M, Mas E, Phillips M, Cleland LG, et al. Specialised pro-resolving mediators of inflammation in inflammatory arthritis. Prostaglandins Leukot Essent Fatty Acids. 2016;107:24. 10.1016/j.plefa.2016.03.004
